| Manchester United | Southampton |
|---|
| GK | David de Gea | | GK | Fraser Forster |
| DR | Daley Blind | | DR | Cedric Soares |
| DR | Luke Shaw | | DR | Matt Targett |
| DR | Eric Bailly | | DR | Virgil van Dijk |
| MD | Marouane Fellaini | | DR | Jose Fonte |
| MD | Paul Pogba | S1 | MD | Oriol Romeu |
| S1 | MD | Juan Mata | | MD | Pierre-Emile Hojbjerg |
| AM | Luis Antonio Valencia | S2 | MD | Steven Davis |
| S3 | FD | Wayne Rooney | | AM | Dusan Tadic |
| S2 | FD | Anthony Martial | | AM | Nathan Redmond |
| FD | Zlatan Ibrahimovic | S3 | FD | Shane Long |
| Substitute | Substitute |
|---|
| S1 | MD | Henrikh Mkhitaryan | S1 | MD | Jordy Clasie |
| S2 | MD | Ander Herrera | S2 | FD | Charlie Austin |
| S3 | DR | Chris Smalling | S3 | FD | Jay Rodriguez |
| Manager | Manager |
|---|
| | Jose Mourinho | | | Claude Puel |