| Southampton | Newcastle United |
|---|
| GK | Alex McCarthy | | GK | Martin Dubravka |
| DR | Cedric Soares | | DR | Paul Dummett |
| DR | Ryan Bertrand | | DR | DeAndre Yedlin |
| DR | Jack Stephens | | DR | Jamaal Lascelles |
| DR | Wesley Hoedt | | DR | Federico Fernandez |
| S2 | MD | Oriol Romeu | | MD | Jonjo Shelvey |
| MD | Mario Lemina | S2 | MD | Mohamed Diame |
| AM | Nathan Redmond | | WR | Matt Ritchie |
| S3 | WR | Mohamed Elyounoussi | | FD | Kenedy |
| FD | Danny Ings | S1 | FD | Ayoze Perez |
| S1 | FD | Charlie Austin | S3 | FD | Yoshinori Muto |
| Substitute | Substitute |
|---|
| S1 | FD | Manolo Gabbiadini | S1 | FD | Salomon Rondon |
| S2 | MD | James Ward-Prowse | S2 | MD | Sung-yueng Ki |
| S3 | FD | Shane Long | S3 | WR | Christian Atsu |
| Manager | Manager |
|---|
| | Mark Hughes | | | Rafael Benitez |