| Manchester United | Southampton |
|---|
| GK | David De Gea | | GK | Alex McCarthy |
| S1 | DR | Luke Shaw | | DR | Ryan Bertrand |
| DR | Aaron Wan-Bissaka | | DR | Kayne Ramsay |
| DR | Victor Lindelof | | DR | Jack Stephens |
| DR | Harry Maguire | | DR | Jan Bednarek |
| MD | Fred | | MD | James Ward-Prowse |
| MD | Bruno Fernandes | | MD | Stuart Armstrong |
| MD | Scott McTominay | | MD | Alex Jankewitz |
| S2 | FD | Edinson Cavani | S2 | WR | Moussa Djenepo |
| S3 | FD | Marcus Rashford | S1 | FD | Danny Ings |
| FD | Mason Greenwood | | FD | Che Adams |
| Substitute | Substitute |
|---|
| S1 | MD | Donny Van De Beek | S1 | WR | Nathan Redmond |
| S2 | FD | Anthony Martial | S2 | DR | Allan Tchaptchet |
| S3 | WR | Daniel James | | | |
| | | | | |
| Manager | Manager |
|---|
| | Ole Gunnar Solskjaer | | | Ralph Hasenhuttl |