| Southampton | Brentford |
|---|
| GK | Fraser Forster | | GK | Alvaro Fernandez |
| DR | Romain Perraud | | DR | Mads Roerslev |
| DR | Lyanco | S2 | DR | Ethan Pinnock |
| DR | Mohammed Salisu | | DR | Pontus Jansson |
| DR | Jan Bednarek | | DR | Kristoffer Ajer |
| MD | Oriol Romeu | | MD | Christian Norgaard |
| MD | James Ward-Prowse | S1 | MD | Shandon Baptiste |
| MD | Ibrahima Diallo | | MD | Vitaly Janelt |
| S1 | WR | Nathan Redmond | S3 | WR | Sergi Canos |
| S3 | FD | Armando Broja | | WR | Bryan Mbeumo |
| S2 | FD | Nathan Tella | | FD | Ivan Toney |
| Substitute | Substitute |
|---|
| S1 | FD | Che Adams | S1 | WR | Yoane Wissa |
| S2 | MD | Stuart Armstrong | S2 | MD | Mathias Jensen |
| S3 | FD | Adam Armstrong | S3 | MD | Finley Stevens |
| Manager | Manager |
|---|
| Mgr | Ralph Hasenhuttl | | Mgr | Thomas Frank |